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Most data come from case reports and small observational series, rather than randomized controlled trials

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Possible Side Effects Common side effects of GLP-1 medications may include: Nausea Vomiting Diarrhea Constipation Stomach pain or discomfort Decreased appetite Indigestion or gas Redness, itching, or soreness at the injection site Most side effects are mild to moderate and may improve as your body adjusts to treatment